BDBM50292952 (+/-)-2-(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)-N-(6-methoxy-2,3-dihydro-1H-inden-1-yl)acetamide::CHEMBL493427

SMILES COc1ccc2CCC(NC(=O)CN3CCc4cc(OC)c(OC)cc4C3Cc3ccc(OC)c(OC)c3)c2c1

InChI Key InChIKey=JWMZPZFSAXVGMK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292952   

TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292952((+/-)-2-(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4...)
Affinity DataIC50: 101nMAssay Description:Antagonist activity at OX2R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292952((+/-)-2-(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4...)
Affinity DataIC50: 19nMAssay Description:Antagonist activity at OX1R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292952((+/-)-2-(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4...)
Affinity DataIC50: 19nMAssay Description:Inhibition of OX1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50292952((+/-)-2-(1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-3,4...)
Affinity DataIC50: 101nMAssay Description:Inhibition of OX2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed