BDBM50292965 2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-diethylacetamide::CHEMBL455137

SMILES CCN(CC)C(=O)CN(c1ccc(C)cc1)S(=O)(=O)c1ccc(cc1)C(C)(C)C

InChI Key InChIKey=OFXZJOZJRALMEK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50292965   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292965(2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at OX1 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292965(2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-di...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at OX2 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292965(2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human OX1 receptor expressed in CHO cells assessed as intercellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292965(2-(4-tert-butyl-N-p-tolylphenylsulfonamido)-N,N-di...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human OX2 receptor expressed in CHO cells assessed as intercellular calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed