BDBM50292966 (R)-2-((S)-3-ethyl-8-(3-fluoro-4-methylphenethyl)-1-methoxy-5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl)-N-methyl-2-phenylacetamide::CHEMBL462433

SMILES CCc1nc(OC)c2[C@H](CCc3ccc(C)c(F)c3)N(CCn12)[C@@H](C(=O)NC)c1ccccc1

InChI Key InChIKey=KJEQHRBTEUGGOC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292966   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292966((R)-2-((S)-3-ethyl-8-(3-fluoro-4-methylphenethyl)-...)
Affinity DataIC50: 49nMAssay Description:Antagonist activity at OX1 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292966((R)-2-((S)-3-ethyl-8-(3-fluoro-4-methylphenethyl)-...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at OX2 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed