BDBM50292968 (R)-2-((S)-8-(3,4-dimethylphenethyl)-3-ethyl-1-methoxy-5,6-dihydroimidazo[1,5-a]pyrazin-7(8H)-yl)-N-methyl-2-phenylacetamide::CHEMBL461772

SMILES CCc1nc(OC)c2C(CCc3ccc(C)c(C)c3)N(CCn12)[C@@H](C(=O)NC)c1ccccc1

InChI Key InChIKey=QNLPHNYLCGQRJK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292968   

TargetOrexin/Hypocretin receptor type 1(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292968((R)-2-((S)-8-(3,4-dimethylphenethyl)-3-ethyl-1-met...)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at OX1 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetOrexin receptor type 2(Human)
Actelion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50292968((R)-2-((S)-8-(3,4-dimethylphenethyl)-3-ethyl-1-met...)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at OX2 receptor by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed