BDBM50292983 1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methyl)phenyl)propanoyl]-N-(4-fluorophenyl)-4-piperidinamine::CHEMBL489297

SMILES CC(C(=O)N1CCC(CC1)Nc1ccc(F)cc1)c1ccc(CN2C[C@H](C)N[C@H](C)C2)cc1

InChI Key InChIKey=DSMHXHKJIOOKIY-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50292983   

TargetCytochrome P450 3A4(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292983(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human CYP3A4 expressed in Escherichia coli using diethoxyfluorescein substrate by time dependent inhibition assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetMotilin receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50292983(1-[2-(4-([(3R,5S)-3,5-Dimethyl-1-piperazinyl]methy...)
Affinity DataEC50:  31.6nMAssay Description:Agonist activity at human recombinant motilin receptor expressed in CHO cells assessed as increase in intracellular calcium by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed