BDBM50293170 (1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-(S)-methyl-5,12,14,16,20,22-hexamethyl-23-oxa-tricyclo[17.3.1.0*2,7*]tricosa-2(7),4,14-triene-3,6,9-trione::CHEMBL499851

SMILES C[C@@H]1[C@H](O)[C@@H](C)[C@H]2O[C@@H]1CC[C@H](C)\C=C(C)\C[C@@H](C)C[C@H](C)C(=O)C(O)C1=C2C(=O)C(=O)C(C)C1=O

InChI Key InChIKey=WIDWOHRBADVMAQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293170   

TargetBcl-2-like protein 1(Human)
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293170((1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-...)
Affinity DataKd:  1.08E+7nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by surface plasmon resonance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Merlion Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293170((1R,12S,16S,19R,20R,21S,22R)-4,8,21-Trihydroxy-10-...)
Affinity DataIC50: 2.30E+5nMAssay Description:Inhibition of interaction between GST-tagged Bcl-xl and Bak by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed