BDBM50293177 CHEMBL505474::N1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol-2-yl)cyclohexane-1,3-diamine

SMILES CC(C)(C)c1cnc(CSc2cnc(NC3CCCC(N)C3)s2)o1

InChI Key InChIKey=NTUMJMHWGWBERQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293177   

TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293177(N1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9 in human HCT116 cells assessed as phosphor-ser2 level of RNA polymerase 2 after 16 hrs by high content cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293177(N1-(5-((5-tert-butyloxazol-2-yl)methylthio)thiazol...)
Affinity DataIC50: 158nMAssay Description:Inhibition of CDK2/cyclin A by IMAP florescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed