BDBM50293182 5-((5-tert-butyloxazol-2-yl)methylthio)-N-(piperidin-4-ylmethyl)thiazol-2-amine::CHEMBL524629

SMILES CC(C)(C)c1cnc(CSc2cnc(NCC3CCNCC3)s2)o1

InChI Key InChIKey=SELYMTMAYFSILA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293182   

TargetCyclin-dependent kinase 2(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293182(5-((5-tert-butyloxazol-2-yl)methylthio)-N-(piperid...)
Affinity DataIC50: 229nMAssay Description:Inhibition of CDK2/cyclin A by IMAP florescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 9(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50293182(5-((5-tert-butyloxazol-2-yl)methylthio)-N-(piperid...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CDK9 in human HCT116 cells assessed as phosphor-ser2 level of RNA polymerase 2 after 16 hrs by high content cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed