BDBM50293281 4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5-dihydro-1H-pyrrol-3-yl)benzoic acid::CHEMBL469574

SMILES CCCN1CC(=C(C1=O)c1ccc(cc1)C(O)=O)c1ccc(cc1)S(C)(=O)=O

InChI Key InChIKey=UOLUFPJCRSHVKK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50293281   

TargetProstaglandin G/H synthase 1(Human)
Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of calcimycin-induced COX1 activityMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50: 409nMAssay Description:Inhibition of COX2 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Mouse)
Chinese Academy of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50293281(4-(4-(4-(methylsulfonyl)phenyl)-2-oxo-1-propyl-2,5...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of COX1 in mouse peritoneal macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed