BDBM50293369 CHEMBL538364::E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic acid Nhydroxyamide

SMILES COc1ccc(cc1)-c1ccc(\C=C\C=C\C(=O)NO)cc1

InChI Key InChIKey=FXNPBRHKCIZIAB-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50293369   

TargetHistone deacetylase 8(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.56E+3nMAssay Description:Inhibition of human HDAC8 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human HDAC6 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC2 in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of HDAC2 in human HeLa cells using KI-104 as substrate after 40 mins by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC10 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC5 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC9 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC3 complexed with NCOR2 using fluorogenic tetrapeptide RHKKAc as susbtrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC4 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC11 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50293369(E,E-5-(4'-Methoxybiphenyl-4-yl)-penta-2,4-dienoic ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human HDAC1 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed