BDBM50293848 (2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(trifluoromethoxy)-1H-indol-1-yl]methyl]phenoxy}isobutyric Acid::CHEMBL564902

SMILES CC(C)[C@H](Oc1cccc(Cn2c(C)c(C(=O)c3ccc(Cl)cc3)c3ccc(OC(F)(F)F)cc23)c1)C(O)=O

InChI Key InChIKey=GDSCCLCHSVBGDJ-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50293848   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293848((2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PPARgamma receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293848((2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human PPARgamma receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293848((2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  360nMAssay Description:Agonist activity at mouse PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293848((2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human PPARalpha receptor expressed in african green monkey COS1 cells co-transfected with fused yeast Gal4-DBD by transactivation...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetPeroxisome proliferator-activated receptor alpha(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50293848((2S)-2-{3-[[3-(4-Chlorobenzoyl)-2-methyl-6-(triflu...)
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of human PPARalpha receptor by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed