BDBM50293943 (R)-5-Chloro-1-(1-cyclopropylethyl)-3-(4,5-dimethoxy-2-methylphenylamino)pyrazin-2(1H)-one::CHEMBL554086

SMILES COc1cc(C)c(Nc2nc(Cl)cn([C@H](C)C3CC3)c2=O)cc1OC

InChI Key InChIKey=PPIJYZSGRSKZDM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293943   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293943((R)-5-Chloro-1-(1-cyclopropylethyl)-3-(4,5-dimetho...)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed