BDBM50293945 (R)-4-Chloro-5-[6-chloro-4-(1-cyclopropylethyl)-3-oxo-3,4-dihydropyrazin-2-ylamino]-2-methylbenzonitrile::CHEMBL563313

SMILES C[C@H](C1CC1)n1cc(Cl)nc(Nc2cc(C#N)c(C)cc2Cl)c1=O

InChI Key InChIKey=MGEHVYLQBJLVAG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293945   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293945((R)-4-Chloro-5-[6-chloro-4-(1-cyclopropylethyl)-3-...)
Affinity DataIC50: 19nMAssay Description:Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed