BDBM50293949 (R)-4-(1-Cyclopropylethyl)-6-[2,6-dichloro-4-(difluoromethoxy)phenylamino]-5-oxo-4,5-dihydropyrazine-2-carbonitrile::CHEMBL556089

SMILES C[C@H](C1CC1)n1cc(nc(Nc2c(Cl)cc(OC(F)F)cc2Cl)c1=O)C#N

InChI Key InChIKey=KZGLLDAIKBBBJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293949   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293949((R)-4-(1-Cyclopropylethyl)-6-[2,6-dichloro-4-(difl...)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [125I]ovine-CRF from CRF1 receptor in rat frontal cortex by rapid filtration techniqueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/23/2012
Entry Details Article
PubMed