BDBM50293960 (R)-5-Chloro-1-[1-(methoxymethyl)propyl]-3-(2,4,6-trimethylphenylamino)pyrazin-2(1H)-one::CHEMBL549329

SMILES CC[C@H](COC)n1cc(Cl)nc(Nc2c(C)cc(C)cc2C)c1=O

InChI Key InChIKey=ZGPMTGOZRGSUNH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50293960   

TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50293960((R)-5-Chloro-1-[1-(methoxymethyl)propyl]-3-(2,4,6-...)
Affinity DataIC50: 1.40nMAssay Description:Displacement of [125I]Tyr-ovine-CRF from CRF1 receptor in rat frontal cortex homogenate by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed