BDBM50294008 (E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl)-4-methyl-N-(5-(tert-butyl)oxazo-3-yl)benzamide::CHEMBL556669

SMILES Cc1ccc(cc1\C=C\n1cnc2c(NC3CC3)ncnc12)C(=O)Nc1cc(on1)C(C)(C)C

InChI Key InChIKey=AASSITCVMHLTIO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294008   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294008((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of human Src kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Ariad Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50294008((E)-3-(2-(6-(Cyclopropylamino)-9H-purin-9-yl)vinyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of wild type human Abl kinase by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed