BDBM50294070 4'-[(3aR,6aR)-5-Isopropylhexahydropyrrolo[3,4-b]pyrrol-1(2H)-yl]-1,10-biphenyl-4-carbonitrile::CHEMBL559446

SMILES CC(C)N1C[C@H]2CCN([C@H]2C1)c1ccc(cc1)-c1ccc(cc1)C#N

InChI Key InChIKey=MMWVEAWQNYFYOU-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294070   

TargetHistamine H3 receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50294070(4'-[(3aR,6aR)-5-Isopropylhexahydropyrrolo[3,4-b]py...)
Affinity DataKi:  42.7nMAssay Description:Displacement of [3H]N-alpha methyl histamine from human cloned histamine H3 receptor expressed in C6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHistamine H3 receptor(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50294070(4'-[(3aR,6aR)-5-Isopropylhexahydropyrrolo[3,4-b]py...)
Affinity DataKi:  851nMAssay Description:Displacement of [3H]N-alpha methyl histamine from rat cortical membrane histamine H3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed