BDBM50294119 CHEMBL561625::N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)acetamide

SMILES CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PZJJOMPTIHBGHO-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50294119   

TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 34nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 530nMAssay Description:Inhibition of human recombinant MMP14 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 34nMAssay Description:Inhibition of MMP9 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 920nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 48nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 39nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of MMP1-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of MMP1 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 12nMAssay Description:Inhibition of MMP2 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed
LigandPNGBDBM50294119(N-hydroxy-2-(N-isobutylbiphenyl-4-ylsulfonamido)ac...)
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of human recombinant ADAM17 by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2010
Entry Details Article
PubMed