BDBM50294122 CHEMBL560837::N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-ylsulfonamido)acetamide

SMILES COc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N(CC(=O)NO)OC(C)C

InChI Key InChIKey=LBKCSOUMADYGHM-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50294122   

Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataKi:  3.80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 10nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 65nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 160nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294122(N-Hydroxy-2-(N-isopropoxy-4'-methoxybiphenyl-4-yls...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed