BDBM50294125 (E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphenylsulfonamido)-N-hydroxyacetamide::CHEMBL563679

SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(\C=C\c2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=ZQBRASLBYJYZLM-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50294125   

TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 74nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 710nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294125((E)-2-(4-(2-(Biphenyl-4-yl)vinyl)-N-isopropoxyphen...)
Affinity DataIC50: 41nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed