BDBM50294126 CHEMBL561038::N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonamido)-acetamide

SMILES CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=WVAIZSKMOMDPIT-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50294126   

TargetMatrix metalloproteinase-9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 110nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant MMP14More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 5.90E+4nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 26nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 66nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50294126(N-Hydroxy-2-(N-isopropoxy-4-phenoxyphenylsulfonami...)
Affinity DataIC50: 63nMAssay Description:Inhibition of MMP13-mediated collagen degradation by SDS-PAGEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed