BDBM50294209 3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimethoxyphenyl)-1-(1-(3-hydroxypropyl)phthalazin-2(1H)-yl)prop-2-en-1-one::CHEMBL549882

SMILES COc1cc(Cc2cnc(N)nc2N)cc(\C=C\C(=O)N2N=Cc3ccccc3C2CCCO)c1OC

InChI Key InChIKey=PUHFIPXGDRIBGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294209   

TargetDihydrofolate reductase(Rat)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294209(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294209(3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimet...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed