BDBM50294210 1-(1-butylphthalazin-2(1H)-yl)-3-(5-((2,4-diaminopyrimidin-5-yl)methyl)-2,3-dimethoxyphenyl)prop-2-en-1-one::CHEMBL562228

SMILES CCCCC1N(N=Cc2ccccc12)C(=O)\C=C\c1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI Key InChIKey=VMZJLCOUDXEVIH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294210   

TargetDihydrofolate reductase(Rat)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294210(1-(1-butylphthalazin-2(1H)-yl)-3-(5-((2,4-diaminop...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of rat DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDihydrofolate reductase(Human)
Oklahoma State University

Curated by ChEMBL
LigandPNGBDBM50294210(1-(1-butylphthalazin-2(1H)-yl)-3-(5-((2,4-diaminop...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed