BDBM50294259 CHEMBL564100::rac-3-((2-chlorophenoxy)(piperidin-4-yl)methyl)pyridine

SMILES Clc1ccccc1OC(C1CCNCC1)c1cccnc1

InChI Key InChIKey=RFKSUPOWTRFCKG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294259   

LigandPNGBDBM50294259(rac-3-((2-chlorophenoxy)(piperidin-4-yl)methyl)pyr...)
Affinity DataIC50: 30nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294259(rac-3-((2-chlorophenoxy)(piperidin-4-yl)methyl)pyr...)
Affinity DataIC50: 9nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294259(rac-3-((2-chlorophenoxy)(piperidin-4-yl)methyl)pyr...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed