BDBM50294264 CHEMBL562244::rac-3-((biphenyl-2-yloxy)(piperidin-4-yl)methyl)pyridine

SMILES C1CC(CCN1)C(Oc1ccccc1-c1ccccc1)c1cccnc1

InChI Key InChIKey=ORQNDGDHUCGODU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294264   

LigandPNGBDBM50294264(rac-3-((biphenyl-2-yloxy)(piperidin-4-yl)methyl)py...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294264(rac-3-((biphenyl-2-yloxy)(piperidin-4-yl)methyl)py...)
Affinity DataIC50: 109nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294264(rac-3-((biphenyl-2-yloxy)(piperidin-4-yl)methyl)py...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed