BDBM50294269 CHEMBL564631::rac-3-((4-(methylthio)phenoxy)(piperidin-4-yl)methyl)pyridine

SMILES CSc1ccc(OC(C2CCNCC2)c2cccnc2)cc1

InChI Key InChIKey=UPHOWEAWENOKEG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294269   

LigandPNGBDBM50294269(rac-3-((4-(methylthio)phenoxy)(piperidin-4-yl)meth...)
Affinity DataIC50: 5.85E+3nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294269(rac-3-((4-(methylthio)phenoxy)(piperidin-4-yl)meth...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294269(rac-3-((4-(methylthio)phenoxy)(piperidin-4-yl)meth...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed