BDBM50294271 5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-methyl pyridine::5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-methylpyridine::CHEMBL559081::rac-3-((2,3-dichloro-6-methylphenoxy)(piperidin-4-yl)methyl)pyridine

SMILES Cc1ccc(cn1)C(Oc1cccc(Cl)c1Cl)C1CCNCC1

InChI Key InChIKey=JAKBXJLCBFHUQX-UHFFFAOYSA-N

Data  11 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50294271   

LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 14nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 590nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 590nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294271(5-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-2-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed