BDBM50294275 CHEMBL559654::rac-3-((2,5-dichlorophenoxy)(piperidin-4-yl)methyl)pyridine

SMILES Clc1ccc(Cl)c(OC(C2CCNCC2)c2cccnc2)c1

InChI Key InChIKey=MNXBENJELVJIHN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294275   

LigandPNGBDBM50294275(rac-3-((2,5-dichlorophenoxy)(piperidin-4-yl)methyl...)
Affinity DataIC50: 84nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294275(rac-3-((2,5-dichlorophenoxy)(piperidin-4-yl)methyl...)
Affinity DataIC50: 7nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294275(rac-3-((2,5-dichlorophenoxy)(piperidin-4-yl)methyl...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed