BDBM50294280 CHEMBL560050::rac-2-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl)-3-methylpyridine

SMILES Cc1cccnc1C(Oc1cccc(Cl)c1Cl)C1CCNCC1

InChI Key InChIKey=ICZPNJDXXLLJEO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294280   

LigandPNGBDBM50294280(rac-2-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl...)
Affinity DataIC50: 400nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294280(rac-2-((2,3-dichlorophenoxy)(piperidin-4-yl)methyl...)
Affinity DataIC50: 11nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed