BDBM50294282 CHEMBL556268::rac-2-((2,3-dichloro-5-methylphenoxy)(piperidin-4-yl)methyl)pyridine

SMILES Cc1ccc(nc1)C(Oc1cccc(Cl)c1Cl)C1CCNCC1

InChI Key InChIKey=OWUWJHDPUJMAGB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50294282   

LigandPNGBDBM50294282(rac-2-((2,3-dichloro-5-methylphenoxy)(piperidin-4-...)
Affinity DataIC50: 48nMAssay Description:Inhibition of [3H]NA uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294282(rac-2-((2,3-dichloro-5-methylphenoxy)(piperidin-4-...)
Affinity DataIC50: 16nMAssay Description:Inhibition of [3H]5-HT uptake at human 5HTT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50294282(rac-2-((2,3-dichloro-5-methylphenoxy)(piperidin-4-...)
Affinity DataIC50: 3.47E+3nMAssay Description:Inhibition of [3H]DA uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed