BDBM50294336 5-amino-2-(4-aminophenylamino)benzenesulfonic acid::CHEMBL560968

SMILES Nc1ccc(Nc2ccc(N)cc2S(O)(=O)=O)cc1

InChI Key InChIKey=VKURVCNKVWKGLX-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294336   

TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50294336(5-amino-2-(4-aminophenylamino)benzenesulfonic acid...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as cleavage of MAPKK by fluorescence peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetRap guanine nucleotide exchange factor 4(Human)
University of Texas Medical Branch

Curated by ChEMBL
LigandPNGBDBM50294336(5-amino-2-(4-aminophenylamino)benzenesulfonic acid...)
Affinity DataIC50: 1.80E+4nMAssay Description:Antagonist activity at recombinant EPAC2 (unknown origin) assessed 8-NBD-cAMP substrate fluorescence intensity by substrate competing assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetBifunctional protein GlmU(Escherichia coli (strain K12))
Mcmaster University

Curated by ChEMBL
LigandPNGBDBM50294336(5-amino-2-(4-aminophenylamino)benzenesulfonic acid...)
Affinity DataKi:  17nMAssay Description:Competitive inhibition of Acetyltransferase activity of Escherichia coli BL21(DE3) GlmU in presence of AcCoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
TargetLethal factor(Bacillus anthracis)
Institute For Medical Research

Curated by ChEMBL
LigandPNGBDBM50294336(5-amino-2-(4-aminophenylamino)benzenesulfonic acid...)
Affinity DataKi:  560nMAssay Description:Inhibition of Bacillus anthracis lethal factor assessed as cleavage of MAPKK by fluorescence peptide cleavage assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed