BDBM50294853 (+/-)-3-{[(cis)-2-Hydroxycyclopentyl]oxy}-5-[4-(methylsulfonyl)phenoxy]-N-1,3-thiazol-2-ylbenzamide::3-((1S,2R)-2-hydroxycyclopentyloxy)-5-(4-(methylsulfonyl)phenoxy)-N-(thiazol-2-yl)benzamide::CHEMBL551911

SMILES CS(=O)(=O)c1ccc(Oc2cc(O[C@H]3CCC[C@H]3O)cc(c2)C(=O)Nc2nccs2)cc1

InChI Key InChIKey=LLIQCVSOVKHPJR-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50294853   

TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50294853(3-((1S,2R)-2-hydroxycyclopentyloxy)-5-(4-(methylsu...)
Affinity DataEC50:  260nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50294853(3-((1S,2R)-2-hydroxycyclopentyloxy)-5-(4-(methylsu...)
Affinity DataEC50:  260nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50294853(3-((1S,2R)-2-hydroxycyclopentyloxy)-5-(4-(methylsu...)
Affinity DataEC50:  110nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHexokinase-4(Human)
Banyu Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50294853(3-((1S,2R)-2-hydroxycyclopentyloxy)-5-(4-(methylsu...)
Affinity DataEC50:  120nMAssay Description:Activation of flag-tagged human recombinant liver glucokinase expressed in Escherichia coli by glucose-6-phosphate dehydrogenase coupled continuous s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed