BDBM50295329 (S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-phenoxypropyl)amino]ethyl}phenyl)thiourea hydrochloride::CHEMBL552368

SMILES O[C@@H](CNCCc1ccc(NC(=S)Nc2cccc(Cl)c2)cc1)COc1ccccc1

InChI Key InChIKey=RSTQEHFTTGCKCJ-UHFFFAOYSA-N

Data  6 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295329   

TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50295329((S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-pheno...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50295329((S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-pheno...)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50295329((S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-pheno...)
Affinity DataEC50:  270nMAssay Description:Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50295329((S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-pheno...)
Affinity DataEC50:  610nMAssay Description:Agonist activity at human cloned adrenergic beta3 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetBeta-2 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50295329((S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-pheno...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human cloned adrenergic beta2 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoassa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetBeta-1 adrenergic receptor(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50295329((S)-1-(3-Chlorophenyl)-3-(4-{2-[(2-hydroxy-3-pheno...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human cloned adrenergic beta-1 receptor expressed in CHO cells assessed as [125I]cAMP accumulation after 2 days by radioimmunoass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed