BDBM50295368 (2R)-1-(4-Bromophenylsulfonyl)-4-(4-fluoro-2-(trifluoromethyl)-phenyl)-2-methylpiperazine::CHEMBL564576

SMILES C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(Br)cc1)c1ccc(F)cc1C(F)(F)F

InChI Key InChIKey=RMSZYZLTJZMDKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295368   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295368((2R)-1-(4-Bromophenylsulfonyl)-4-(4-fluoro-2-(trif...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human 11betaHSD1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Mouse)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50295368((2R)-1-(4-Bromophenylsulfonyl)-4-(4-fluoro-2-(trif...)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse 11betaHSD1 expressed in CHO cells in presence of 10 % (v/v) human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed