BDBM50295568 3,4-Dihydro-8-methyl-3-[2-(6-methylnaphthoyl)]-2H-pyrido[1,2-a]pyrimidine perchlorate::CHEMBL562458

SMILES Cc1ccn2CC(CN[c+]2c1)C(=O)c1ccc2cc(C)ccc2c1

InChI Key InChIKey=DJTIRUGMSOSCKU-UHFFFAOYSA-O

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50295568   

TargetNitric oxide synthase, inducible(Mouse)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50295568(3,4-Dihydro-8-methyl-3-[2-(6-methylnaphthoyl)]-2H-...)
Affinity DataKi:  2.30E+4nMAssay Description:Inhibition of mouse iNOS expressed in insect Sf9 cells by competitive binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Christian-Albrechts-University of Kiel

Curated by ChEMBL
LigandPNGBDBM50295568(3,4-Dihydro-8-methyl-3-[2-(6-methylnaphthoyl)]-2H-...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of mouse recombinant iNOS expressed in Escherichia coli assessed as conversion of [gamma-14C]L-arginine to [14C]L-citrulline by radioactiv...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed