BDBM50295656 CHEMBL569368::dodecylcarbamic acid 4-(1,2,3-thiadiazol-4-yl)phenylester

SMILES CCCCCCCCCCCCNC(=O)Oc1ccc(cc1)-c1csnn1

InChI Key InChIKey=GEIAMKWXBDGPKE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295656   

TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50295656(dodecylcarbamic acid 4-(1,2,3-thiadiazol-4-yl)phen...)
Affinity DataIC50: 82nMAssay Description:Inhibition of FAAH-mediated hydrolysis of [3H]anandamide in rat RBL2H3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Human)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50295656(dodecylcarbamic acid 4-(1,2,3-thiadiazol-4-yl)phen...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant MGL by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50295656(dodecylcarbamic acid 4-(1,2,3-thiadiazol-4-yl)phen...)
Affinity DataIC50: 12nMAssay Description:Inhibition of FAAH in Wistar rat cerebral membrane by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMonoglyceride lipase(Rat)
University of Kuopio

Curated by ChEMBL
LigandPNGBDBM50295656(dodecylcarbamic acid 4-(1,2,3-thiadiazol-4-yl)phen...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MGL in Wistar rat cerebral membrane by HPLCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed