BDBM50295752 4-(6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrrolo[3,2-b]pyridin-1-ylsulfonyl)benzo[c][1,2,5]oxadiazole::CHEMBL554497

SMILES O=S(=O)(c1cccc2nonc12)n1ccc2ncc(cc12)-c1cnn(c1)C1CCNCC1

InChI Key InChIKey=JEGPFJOMJNNNAL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50295752   

TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295752(4-(6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrro...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295752(4-(6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrro...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295752(4-(6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrro...)
Affinity DataIC50: 130nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295752(4-(6-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)-1H-pyrro...)
Affinity DataIC50: 200nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed