BDBM50295758 1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(piperazin-1-yl)-1H-pyrrolo[3,2-b]pyridine::CHEMBL560575

SMILES Clc1nc2sccn2c1S(=O)(=O)n1ccc2ncc(cc12)N1CCNCC1

InChI Key InChIKey=AVOMNNXOQGDQAW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295758   

TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295758(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human recombinant His-tagged c-Met by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295758(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of c-Met phosphorylation in human MKN45 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Ucb Pharma

Curated by ChEMBL
LigandPNGBDBM50295758(1-(6-chloroimidazo[2,1-b]thiazol-5-ylsulfonyl)-6-(...)
Affinity DataIC50: 1.71E+3nMAssay Description:Inhibition of c-Met phosphorylation in human A549 cells after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed