BDBM50295872 5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine::CHEMBL552324

SMILES Cn1cc(-c2nc(N)ncc2I)c2ccccc12

InChI Key InChIKey=UBGVTDYQKHFKNI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50295872   

LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50: 400nMAssay Description:Inhibition of rat recombinant DYRK1A expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of human recombinant CDK5/p25More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Rat)
Clermont Universit£

Curated by ChEMBL
LigandPNGBDBM50295872(5-Iodo-4-(1-Methyl-1H-indol-3-yl)pyrimidin-2-amine...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of rat recombinant Erk2More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed