BDBM50295904 3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-(1Hpyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione::CHEMBL558512

SMILES O=C1NC(=O)C(=C1c1cn(CCn2ccnc2)c2ccccc12)n1ccc2ncccc12

InChI Key InChIKey=QPIQPTBXCPADIC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50295904   

TargetProtein kinase C epsilon type(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50295904(3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant PKCE expressed in Bac-to Bac baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50295904(3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant IKK2 expressed in Bac-to Bac baculovirus systemMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50295904(3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant Aurora A expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50295904(3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant MEK1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50295904(3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant ERK1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50295904(3-(1-(2-(1H-Imidazol-1-yl)ethyl)-1H-indol-3-yl)-4-...)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant GST-GSK3beta expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2010
Entry Details Article
PubMed