BDBM50296075 CHEMBL564931::sodium(3R,5S,E)-7-(4-(3-(2-fluorophenyl)pentan-3-yl)-2-isopropylphenyl)-3,5-dihydroxyhept-6-enoate

SMILES CCC(CC)(c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C)c1ccccc1F

InChI Key InChIKey=XGHUUHXYQJHQGG-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296075   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rat)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50296075(sodium(3R,5S,E)-7-(4-(3-(2-fluorophenyl)pentan-3-y...)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed