BDBM50296463 1-(4-chlorophenyl)-2-(5-(furan-2-yl)-4-vinyl-4H-1,2,4-triazol-3-ylthio)ethanone::CHEMBL562693

SMILES Clc1ccc(cc1)C(=O)CSc1nnc(-c2ccco2)n1C=C

InChI Key InChIKey=MHZJLCNCTVELCZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296463   

TargetM-phase inducer phosphatase 2(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296463(1-(4-chlorophenyl)-2-(5-(furan-2-yl)-4-vinyl-4H-1,...)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of N-terminal 6xHis-tagged (378-566) catalytic domain of Cdc25B expressed in Escherichia coli after 20 mins by by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetM-phase inducer phosphatase 1(Human)
Sejong University

Curated by ChEMBL
LigandPNGBDBM50296463(1-(4-chlorophenyl)-2-(5-(furan-2-yl)-4-vinyl-4H-1,...)
Affinity DataIC50: 1.45E+4nMAssay Description:Inhibition of N-terminal 6xHis-tagged human Cdc25A (336-523) catalytic domain expressed in Escherichia coli after 20 mins by fluorescent plate reader...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed