BDBM50296547 1-(2-(quinolin-8-ylmethylamino)ethyl)-8,9-dihydro-3H-pyrrolo[3,2-f]isoquinolin-6(7H)-one::CHEMBL559994

SMILES O=C1NCCc2c1ccc1[nH]cc(CCNCc3cccc4cccnc34)c21

InChI Key InChIKey=NXDMLDJTEYAEAK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50296547   

TargetPoly [ADP-ribose] polymerase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50296547(1-(2-(quinolin-8-ylmethylamino)ethyl)-8,9-dihydro-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of PARP1 in human HeLa cells by microplate scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed