BDBM50296676 (E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)-propenone::CHEMBL564089

SMILES COc1ncc(\C=C\C(=O)C23CC4CC(CC(C4)C2)C3)cc1C

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296676   

TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296676((E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)...)
Affinity DataKi:  294nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296676((E)-1-Adamantan-1-yl-3-(4-methoxy-3-methyl-phenyl)...)
Affinity DataKi:  5.15E+3nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed