BDBM50296679 Adamantan-1-yl-[2-(6-methoxy-pyridin-3-yl)-cyclopropyl]-methanone::CHEMBL551469

SMILES COc1ccc(cn1)C1CC1C(=O)C12CC3CC(CC(C3)C1)C2

InChI Key

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296679   

TargetMetabotropic glutamate receptor 1(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296679(Adamantan-1-yl-[2-(6-methoxy-pyridin-3-yl)-cyclopr...)
Affinity DataKi:  304nMAssay Description:Displacement of [3H]E-3-(2-chloro-8-methylquinolin-3-yl)-1-(thiophen-2-yl)prop-2-en-1-one from mGluR1 in rat cerebellar membrane after 14 to 16 hrs b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
Merz Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50296679(Adamantan-1-yl-[2-(6-methoxy-pyridin-3-yl)-cyclopr...)
Affinity DataKi:  1.84E+4nMAssay Description:Displacement of [3H]MPEP from mGluR5 in rat cortical membrane after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed