BDBM50297269 1-(5-Fluoro-2,3-dihydro-indol-1-yl)-2-(1H-indol-3-yl)-ethane-1,2-dione::CHEMBL540971

SMILES Fc1ccc2N(CCc2c1)C(=O)C(=O)c1c[nH]c2ccccc12

InChI Key InChIKey=ALLRODMPOJXNSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297269   

TargetCyclin-dependent kinase 4(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50297269(1-(5-Fluoro-2,3-dihydro-indol-1-yl)-2-(1H-indol-3-...)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
University of Leicester

Curated by ChEMBL
LigandPNGBDBM50297269(1-(5-Fluoro-2,3-dihydro-indol-1-yl)-2-(1H-indol-3-...)
Affinity DataIC50: 7.90E+5nMAssay Description:Inhibition of human CDK2/ Cyclin A catalytic subunit expressed in Sf9 insect cells assessed as histone H1 phosphorylation-associated depletion in ATP...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed