BDBM50297372 3-(3-(tert-butylthio)-5-(pyridin-2-ylmethoxy)-1-(4-(pyrimidin-5-yl)benzyl)-1H-indol-2-yl)-2,2-dimethylpropanoic acid::CHEMBL555207

SMILES CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(cc2)-c2cncnc2)c2ccc(OCc3ccccn3)cc12

InChI Key InChIKey=VVQHJQAFIKPKKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50297372   

TargetArachidonate 5-lipoxygenase-activating protein(Human)
Amira Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50297372(3-(3-(tert-butylthio)-5-(pyridin-2-ylmethoxy)-1-(4...)
Affinity DataIC50: 7.70nMAssay Description:Displacement of [3H]3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzyl-indol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed