BDBM50298001 (+/-)-5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid::5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrobromide::5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-indazole-3-carboxylic acid, hydrochloride::CHEMBL1237147::CHEMBL539398

SMILES OC(=O)c1n[nH]c2CCC(Cc12)c1cccnc1F

InChI Key InChIKey=JQOSYJBFVAFNNY-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50298001   

TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 370nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 600nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in absence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataIC50: 850nMAssay Description:Displacement of [3H]niacin from human niacin receptor expressed in CKO-K1 cells in presence of 5% human serumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  2.30E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50298001(5-(2-fluoropyridin-3-yl)-4,5,6,7-tetrahydro-1H-ind...)
Affinity DataEC50:  4.50E+3nMAssay Description:Agonist activity at human niacin receptor expressed in CKO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2012
Entry Details Article
PubMed