BDBM50298018 CHEMBL549864::N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)ethyl)pivalamide

SMILES CC(C)(C)C(=O)NCCC1CC(=NO1)c1ccc(O)c(F)c1

InChI Key InChIKey=LXIKXZQMCLIABU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298018   

TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298018(N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298018(N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298018(N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisox...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed