BDBM50298021 4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydroisoxazol-5-yl)ethyl)benzamide::CHEMBL554732

SMILES Oc1ccc(cc1F)C1=NOC(CCNC(=O)c2ccc(F)cc2)C1

InChI Key InChIKey=UAPQSURMMCXUFR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50298021   

TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298021(4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of MIF in human THP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298021(4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of dopachrome tautomerase activity of human recombinant MIFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed
TargetMacrophage migration inhibitory factor(Human)
Piramal Life Sciences

Curated by ChEMBL
LigandPNGBDBM50298021(4-fluoro-N-(2-(3-(3-fluoro-4-hydroxyphenyl)-4,5-di...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spontaneous secretion/release/recognition of MIF from freshly isolated human PBMC by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2010
Entry Details Article
PubMed